人工夜光和甲状腺癌的关系
Athanasios Tselebis1, Eftychia Koukkou2, Charalampos Milionis2
1Department of Psychiatry, "Sotiria" General Chest Diseases Hospital, Athens GR-11527, Greece.
World journal of methodology
|April 5, 2024
概括
夜间人工光 (ALN) 暴露与甲状腺癌 (TC) 发病率没有直接相关. 较高的GDP和医疗支出可能会影响TC风险和诊断,而不是ALN本身.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 在瘤学瘤学.
背景情况:
- 近几十年来,甲状腺癌 (TC) 的发病率在全球范围内有所增加.
- 夜间暴露于人工光线 (ALN) 是癌症的潜在环境风险因素.
- 调查ALN和TC之间的关系对于公共卫生至关重要.
研究的目的:
- 检查ALN暴露对甲状腺癌发病率的全球影响.
- 评估ALN作为与TC相关的环境污染物.
- 探索ALN-TC协会中的潜在混因素.
主要方法:
- 全球卫星ALN数据的分析.
- 与甲状腺癌发病率数据的相关性 (调整后标准化率 - ASR).
- 包括癌症注册表 (QCR) 的质量,国内生产总值 (GDP) 和人均卫生支出 (HEP) 作为共同变量.
主要成果:
- 在较高的ASR和ALN暴露之间发现了初始相关性,特别是在高GDP/HEP国家.
- 在不同的QCR水平中观察到ASR的显著差异.
- 在控制GDP/HEP或QCR时,ASR和ALN之间没有显著的关联.
结论:
- 较高的GDP和医疗支出可能与不良健康状况和TC风险有关,而不是直接的ALN影响.
- 局限性包括横截面数据和ALN作为社会经济代理.
- 光污染可能间接与有利于癌症的生活方式有关;更高的GDP/HEP可能会改善TC诊断和报告.
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