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在炎症性肠病中静脉血栓栓塞的亚型:全国性的评估
Yassine Kilani1, Mohammad Aldiabat2, Chee Yao Lim1
1Department of Medicine, Lincoln Medical Center/Weill Cornell Medicine, New York, NY, USA.
Clinical research and clinical trials
|April 5, 2024
概括
患有炎症性肠病 (IBD) 的人患深静脉血栓症 (DVT),门静脉血栓症 (PVT) 和脑静脉鼻腔血栓症 (CVST) 的风险更高. 这种增加的风险与更长的住院时间有关,但不增加死亡率.
科学领域:
- 胃肠病学 胃肠病学
- 血管医学 血管医学
- 流行病学 流行病学
背景情况:
- 关于炎症性肠病 (IBD) 患者特定静脉血栓栓塞 (VTE) 亚型风险的数据有限.
- 了解这些风险对于临床管理和患者护理至关重要.
研究的目的:
- 评估炎症性肠病 (IBD) 与各种静脉瘤亚型风险之间的关联.
- 为了比较VTE亚型发病率在住院患者和IBD没有.
主要方法:
- 使用全国住院患者样本数据库 (2016-2020年).
- 应用多变量回归分析来比较VTE亚型的几率.
- 包括深静脉血栓症 (DVT),肺栓塞 (PE),门静脉血栓症 (PVT),Budd Chiari综合征 (BCS),静脉血栓症 (RVT) 和大脑静脉鼻血栓症 (CVST).
主要成果:
- 炎症性肠病 (IBD) 与深静脉血栓症 (DVT),门静脉血栓症 (PVT) 和脑静脉鼻血栓症 (CVST) 的几率增加有关.
- 肺栓塞 (PE),Budd Chiari综合征 (BCS) 或静脉血栓症 (RVT) 的几率没有显著增加.
- 与克罗恩病 (CD) 患者相比,性结肠炎 (UC) 患者对大多数VTE亚型的风险更高. IBD患者经历了更长的住院时间.
结论:
- 炎症性肠病 (IBD) 与DVT,PVT和CVST住院的风险更高有关.
- 临床医生应在IBD患者中保持对VTE的高度怀疑指数.
- IBD的存在与VTE相关入院的住院时间增加有关.
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