关于纳米颗粒用于核酸输送的最新专利和技术的概述
Larissa Moraes Dos Santos Fonseca1,2, Bruna Aparecida Souza Machado1,2, Fabricia Oliveira Oliveira1,2
1FIOCRUZ Bahia, Gonçalo Moniz Institute (IGM) Oswaldo Cruz Foundation (Fiocruz), Salvador, BA, Brazil.
Expert opinion on therapeutic patents
|April 5, 2024
概括
纳米粒子 (NP) 对于提供核酸疗法至关重要,克服遗传疾病和疫苗的交付挑战. 本综述分析了NP专利趋势,以指导在这个快速发展的领域的创新.
科学领域:
- 生物技术和制药科学 生物技术和制药科学
- 纳米技术用于药物输送.
- 治疗药物的知识产权
背景情况:
- 基于核酸的治疗方法对遗传疾病和疫苗有希望.
- 核酸的有效输送仍然是一个重大挑战.
- 纳米粒子 (NP) 是有效的核酸输送的关键载体.
研究的目的:
- 为核酸输送中的NP提供全球专利格局的全面概述.
- 分析NP专利中的时间趋势,地理分布,市场动态和关键技术领域.
- 为治疗应用提供基于NP的交付系统的进步和潜力提供见解.
主要方法:
- 专利格局分析专利格局分析
- 审查专利构成,申请和制造方面.
- 分析时间趋势,保护地点和市场动态.
主要成果:
- 核酸输送中的NP的投资和专利活动大幅增加.
- 确定关键的技术领域和有影响力的专利.
- 概述市场动态和全球保护战略.
结论:
- 了解专利环境对于促进创新和指导战略决策至关重要.
- 克服临床翻译挑战需要强有力的证据,监管合规性和简化制造.
- 进一步的研究和全球合作对于推进基于NP的核酸输送技术至关重要.
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