心血管疾病患者的癌症史和身体功能
Takashi Miki1, Kentaro Kamiya2,3, Nobuaki Hamazaki4
1Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Sagamihara, Kanagawa, Japan.
Heart and vessels
|April 5, 2024
概括
癌症史与心血管疾病 (CVD) 患者的身体功能下降有关. 癌症史和身体功能不佳的组合显著增加了这些患者的死亡风险.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
背景情况:
- 骨肌肉质量损失是癌症和心血管疾病 (CVD) 的常见结果,对患者的预后产生负面影响.
- 了解癌症史,身体功能和心血管疾病患者的结果之间的相互作用对于改善护理至关重要.
研究的目的:
- 调查心血管疾病患者癌症史和身体功能之间的关联.
- 检查癌症史和身体功能对心血管疾病患者预后的综合影响.
主要方法:
- 3,796名心血管疾病患者的回顾性审查,评估在出院时的身体功能 (步行速度,6分钟步行距离 [6MWD]).
- 多重线性回归分析癌症史与身体功能的关联.
- 卡普兰-梅尔曲线和考克斯回归来评估基于癌症史和身体功能水平的预后关联.
主要成果:
- 癌症史独立地与明显较低的步行速度和6MWD性能有关.
- 患有癌症病史和身体功能低下的患者的死亡风险明显更高.
- 调整后的分析显示,癌症病史和低步行速度 (HR: 1.93) 或低6MWD (HR: 1.61) 的患者死亡风险比增加.
结论:
- 癌症史与心血管疾病患者的身体功能下降有关.
- 癌症病史和身体功能不佳的同时发生是心血管疾病患者预后不佳和死亡率增加的重要预测因素.
相关概念视频
Assessment of the Cardiovascular System I: Subjective Data
323
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
323
Cancer Prevention
6.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.2K
Cancer Survival Analysis
345
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
345
Exercise and Cardiovascular Response
802
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
802
Psychoneuroimmunology: Diabetes and Cancer
28
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
28
Psychoneuroimmunology: Cardiovascular Disease
30
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
30


