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Updated: Jun 29, 2025

An Iodide-Yellow Fluorescent Protein-Gap Junction-Intercellular Communication Assay
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基于Yo-Pro1的细胞质吸收的Connexin43半通道功能评估

Raf Van Campenhout1, Julen Sanz-Serrano1, Axelle Cooreman1

  • 1Entity of In Vitro Toxicology and Dermato-Cosmetology, Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Brussels, Belgium.

Methods in molecular biology (Clifton, N.J.)
|April 5, 2024
PubMed
概括

连接素半通道对细胞通信至关重要,当打开时可以触发炎症和细胞死亡. 这项研究详细介绍了一种使用Yo-Pro-1染料评估它们活性的方法,有助于开发新的治疗阻断剂.

关键词:
蜂通讯 蜂通讯是通过蜂通讯进行的.连接蛋白质是连接蛋白的蛋白质.连接43半通道功能.对Yo-Pro1的细胞溶液吸收连因素的病毒转导43

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相关概念视频

Gap Junctions01:37

Gap Junctions

Multicellular organisms employ a variety of ways for cells to communicate with each other. Gap junctions are specialized proteins that form pores between neighboring cells in animals, connecting the cytoplasm between the two, and allowing for the exchange of molecules and ions. They are found in a wide range of invertebrate and vertebrate species, mediate numerous functions including cell differentiation and development, and are associated with numerous human diseases, including cardiac and...
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