饮食中的氨酸调节了Culter alburnus的生长性能,抗氧化能力和免疫反应
Xinyuan Mao1,2, Yue Wang1,2, Ting Zhang1
1Key Laboratory of Freshwater Fisheries and Germplasm Resources Utilization, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi, 214081, China.
Fish physiology and biochemistry
|April 5, 2024
概括
食中补充氨酸可显著增强顶口鱼的生长,抗氧化能力和免疫反应. 氨酸的最佳水平 (2.28-2.81%) 改善了鱼的健康和性能.
科学领域:
- 水产养殖营养水产养殖营养
- 鱼类生理学 鱼类生理学
- 免疫学 免疫学 免疫学
背景情况:
- 科尔特·阿尔伯努斯 (Culter alburnus) 容易受到环境压力因素的影响.
- 阿基因是氧化的前体,在减轻氧化应激和增强鱼类抗氧化和免疫防御方面发挥着至关重要的作用.
研究的目的:
- 为了研究不同食中阿金宁水平对Culter alburnus的生长性能,肝脏抗氧化能力和免疫参数的影响.
- 为了确定青少年顶口培养的最佳食氨酸需求.
主要方法:
- 给C. alburnus幼提供了五种实验性饮食,含有明显的氨酸水平 (1.96%至3.09%),为期8周.
- 增长绩效指标 (最终重量,体重增长率,特异性增长率,料转换率) 被测量.
- 分析了肝脏的抗氧化剂指数 (超氧化脱酶,谷氨,马隆迪甲基) 和免疫基因表达 (Nrf2/Keap1通路,MyD88,IL-1β,TGF-β,C3,C4).
主要成果:
- 摄入2.28-2.81%的食氨酸水平显著改善了生长性能 (最终体重,体重增加率,特异性增长率) 并降低了料转化率.
- 观察到增强的肝脏抗氧化能力,增加了超氧化脱酶和谷氨水平,减少了甲.
- 氨酸补充剂调节了Nrf2/Keap1通路,调高了抗氧化酶表达 (Mn-SOD,CAT),并通过调低促炎标记物 (MyD88,IL-1β) 和调高抗炎和补充基因 (TGF-β,C3,C4) 来增强免疫反应.
结论:
- 在2.28%和2.81%之间的食中氨酸水平有利于改善Culter alburnus的生长,抗氧化能力和免疫反应.
- 据估计,最佳的食氨酸需求为特定生长率的2.55%和料转化率的2.53%,分别占食蛋白质的5.43%和5.38%.
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