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β细胞胰岛素抵抗在脂肪诱导的β细胞功能障碍中起因作用 在体外和体外

Aleksandar Ivovic1, Justin Hou Ming Yung1, Andrei I Oprescu2

  • 1Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.

Endocrinology
|April 5, 2024
PubMed
概括

高含量的自由脂肪酸会损害胰腺β细胞中的胰岛素信号传递. 贝塔细胞中的胰岛素抵抗有助于这种功能障碍,如大鼠和小鼠的保护实验所示.

关键词:
贝塔细胞的功能障碍贝塔细胞的胰岛素耐药性贝塔细胞对胰岛素进行信号传递.脂肪毒性 脂肪毒性 脂肪毒性油酸是一种油酸.橄油橄油的使用方法

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