ω3-PUFA通过上调 miR-107 向 PIEZO1/NFκB p65 来缓解神经炎症

Hailin Liu1, Lian Zhou2, Pengcheng Yi1

  • 1Department of Anesthesiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China; Key Laboratory of Anesthesiology of Jiangxi Province, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China; Jiangxi Province Key Laboratory of Molecular Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

概括

欧米茄-3多不和脂肪酸 (ω3-PUFA) 通过增加miR-107.7,降低神经炎症并改善认知功能. 这种微RNA向PIEZO1,抑制NFκB通路并减少大脑中的炎症反应.

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