中性粒细胞驱动的M2类巨细胞在全身性硬化症模型中对皮肤纤维化至关重要

Pixia Gong1, Yayun Ding2, Wen Li2

  • 1The First Affiliated Hospital of Soochow University, State Key Laboratory of Radiation Medicine and Protection, Institutes for Translational Medicine, Suzhou Medical College of Soochow University, Suzhou, China; Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, NHC Key Laboratory of Thrombosis and Hemostasis, The First Affiliated Hospital of Soochow University, Suzhou, China.

概括

中性粒细胞通过中性粒细胞外细胞陷驱动M2类巨细胞在全身性硬化症 (SSc) 中的积累. 准这种中性粒细胞-巨细胞-纤维化轴为SSc.提供了一种新的治疗策略.