100名患有功能性视力损失的患者的观察性队列研究:临床特征和与其他功能神经系统疾病的比较
Mitchell Lawlor1, Brandon Huynh2, Kate Humphreys3
1Save Sight Institute, Sydney, Australia; Faculty of Medicine and Health, University of Sydney, Sydney, Australia; Department of Ophthalmology, Sydney Eye Hospital, Sydney, Australia.
概括
功能性视力损失通常影响年轻女性,并且经常与精神病,医疗和眼部疾病有关. 这项研究强调了功能性视力损失和其他功能神经系统疾病之间的相似之处.
科学领域:
- 神经科学是一个神经科学.
- 眼科医生 眼科 眼科
- 精神病学是一个精神病学.
背景情况:
- 功能神经系统疾病 (FNDs) 越来越多地被理解.
- 功能性视力丧失 (FVL) 是一种需要进一步调查的特定类型的FND.
- 将FVL与其他FND进行比较可以阐明共享的特征.
研究的目的:
- 为了提高对功能性视力损失的理解.
- 将FVL患者的特征与其他功能综合征患者的特征进行比较.
- 确定患者人口统计和病史中的共同点和差异.
主要方法:
- 进行了前性和后性观察队列研究.
- 从伦敦3家医院的神经眼科诊所招募了157名参与者.
- 参与者包括100名FVL,21名有机视力损失,36名健康对照,所有通过神经眼科检查,神经成像和电生理学证实.
主要成果:
- FVL队列主要是女性 (74%),平均年龄为40.0±16岁.
- 50%的FVL患者有先前的精神病诊断 (最常见的抑郁症),87%有被诊断的医学疾病.
- 26%的总队列有机视力损失与功能覆盖,35%报告了额外的功能症状.
结论:
- 患有FVL的患者与其他FND患者有共同的特征,通常是年轻女性.
- FVL与更高的精神病,医学和眼部并发病率有关.
- 导致压力因素,抑郁症和有机眼睛问题在患有FVL的个体中更为普遍.
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