高血压与未来骨折风险增加有关,但不是反之亦然
Xiang-Peng Du1, Mei-Liang Zheng2, Xin-Chun Yang3
1Department of Cardiology, Weihaiwei People's Hospital, Weihai, Shandong, China.
Scientific reports
|April 5, 2024
概括
高血压史增加了成年人未来骨折的风险. 然而,经历骨折似乎不会增加晚年患高血压的可能性.
科学领域:
- 流行病学 流行病学
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
背景情况:
- 高血压和骨折风险之间的关系是复杂的,在研究中经常出现差异.
- 之前的研究主要关注高血压预测未来骨折,对骨折预测事件高血压的关注较少.
研究的目的:
- 调查高血压和骨折风险之间的双向关联.
- 为了确定高血压史是否预测未来的骨折.
- 检查骨折史是否预测高血压的发生率.
主要方法:
- 利用来自中国健康和营养调查 (CHNS) 预期队列 (1997-2015) 的数据.
- 包括1997年,2000年,2004年或2006年的基线数据的成年参与者,结果评估于2015年.
- 采用Cox的比例危险模型来计算调整的危险比率 (HR) 和95%的置信区间 (CI).
主要成果:
- 在所有研究期间,高血压史与未来骨折的风险增加有关 (例如,调整后HR为1.40,95%CI为2000-2015年的1.04-1.88).
- 骨折史没有显示出与高血压发病率的显著关联 (例如,调整后HR为1.09,95%CI为0.85-1.38为2006-2015).
结论:
- 患有高血压的病史是未来骨折的重要危险因素.
- 骨折似乎不是发展高血压的危险因素.
- 研究结果强调了管理高血压的重要性,以预防骨折.
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