探索脊髓肌肉缩患者认知功能的变化:一个范围审查
Gabriele Giannotta1, Marta Ruggiero1, Marta De Rinaldis1
1Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation), Associazione "La Nostra Famiglia" - IRCCS "E. Medea", Scientific Hospital for Neurorehabilitation, Brindisi, Italy.
概括
大多数脊椎肌肉缩 (SMA) 患者的认知能力与一般人群相当. 需要进一步的研究才能充分理解SMA的认知参与,特别是在I型患者中.
科学领域:
- 神经学 神经学
- 遗传学 是一个遗传学.
- 康复医学 康复医学 康复医学
背景情况:
- 在脊髓肌肉缩 (SMA) 中的认知功能仍然不太了解.
- 需要进行研究来澄清SMA患者的认知参与及其与临床特征的关系.
研究的目的:
- 探索最近关于脊髓肌肉缩 (SMA) 患者认知结果的发现.
- 确定评估这一群体认知功能的常见措施.
- 检查SMA临床特征和认知能力之间的相关性.
主要方法:
- 根据乔安娜·布里格斯研究所的方法进行了范围审查.
- 在两个数据库和参考列表中进行文献搜索,直到2023年12月.
- 包括的研究是同行评审的,以英语语言的文章专注于SMA和认知功能.
主要成果:
- 从1452个初始记录中,包括了13篇文章.
- 大多数研究表明,SMA患者的认知能力在正常范围内.
- 第一种类型的SMA患者可能会表现出受影响的认知领域,而II类和III类型的SMA似乎影响较小.
结论:
- 大多数脊柱肌缩 (SMA) 患者表现出与一般人群相似的认知能力.
- 认知影响因SMA类型而异,在I型中可能涉及特定领域.
- 需要进一步的研究,以全面了解SMA的认知功能.
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