年龄对中枢淋巴结的影响 参与甲状腺 papillary 癌症
Shadi Awny1, Ahmed Abdallah1, Islam H Metwally1
1Surgical Oncology Department, Oncology Center Mansoura University (OCMU), Mansoura, Egypt.
BMC cancer
|April 5, 2024
概括
年轻的乳头甲状腺癌患者 (<20岁) 患中枢淋巴结转移的风险较高,但在全甲状腺切除和中枢淋巴结剖开后,无病生存率更好.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 内分泌手术 内分泌手术
背景情况:
- 乳头甲状腺癌 (PTC) 管理通常涉及到全甲状腺切除术.
- 中枢淋巴结解剖 (CLND) 在PTC中的作用仍然是争论的主题.
- 了解患者年龄和淋巴结状况之间的关系对于治疗决策至关重要.
研究的目的:
- 为了研究患者年龄与皮皮性甲状腺癌中中枢淋巴结状况之间的相关性.
- 分析年龄对侧淋巴结参与和疾病复发的影响.
主要方法:
- 对315名经过全甲状腺切除术和CLND的PTC患者进行了回顾性分析.
- 患者被分为三个年龄组:<20,20-40,和>40岁.
- 中枢和侧侧淋巴结状况,收获数量和无病生存率 (DFS) 与年龄组的相关性.
主要成果:
- 年龄在20岁以下的患者中,中枢淋巴结阳性的患病率较高.
- 侧侧淋巴结收获在<20岁组显着更大,而不会影响阳性节点数.
- 年龄较小的年龄组表现出更长的无病生存期 (DFS).
结论:
- 20岁以下的患者有较高的中枢淋巴结恶性瘤的可能性和较高的侧节结产量.
- 尽管中枢节点阳性较高,但年轻患者的复发率较低.
- 年龄是影响淋巴结状况和乳头甲状腺癌的结果的一个重要因素.
相关概念视频
Secondary Lymphoid Organs
1.5K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
1.5K
Cells of the Adaptive Immune Response
983
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
983


