睡眠质量与干眼疾病之间的关联:文献综述和元分析
1Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Capital Medical University, No. 1 Dong Jiao Min Xiang, Dong Cheng District, 100730, Beijing, China.
BMC ophthalmology
|April 5, 2024
概括
干眼患者的睡眠质量较差,包括睡眠延迟时间较长,睡眠不足或睡眠过多的风险增加. 这一系统性审查强调了干眼疾病和睡眠障碍之间的显著联系.
科学领域:
- 眼科和睡眠医学 眼科和睡眠医学
- 系统性审查和元分析
- 观察研究分析 观察研究分析
背景情况:
- 干眼病 (DED) 是一种普遍存在的眼睛表面疾病.
- 睡眠质量对整体健康和福祉至关重要.
- DED和睡眠障碍之间的关系需要全面调查.
研究的目的:
- 系统地审查和综合现有关于干眼和睡眠质量之间关联的证据.
- 通过元分析量化干眼对各种睡眠参数的影响.
主要方法:
- 在PubMed,EMBASE,Cochrane,Web of Science和灰色文学中进行全面的文献搜索.
- 包括2023年4月之前发表的观察性研究.
- 使用STAT15软件进行的元分析,汇总了21项涉及419,218名参与者的研究数据.
主要成果:
- 与健康对照组相比,干眼患者报告主观睡眠质量明显差.
- 干眼患者的睡眠延迟时间更长,睡眠时间不健康 (睡眠不足或睡眠过度) 的风险更高.
- 在干眼组中观察到匹兹堡睡眠质量指数 (PSQI) 分数 (WMD = 1.78) 和爱普沃思睡眠度量 (ESS) 分数 (WMD = 3.02) 的升高,这表明睡眠质量较差,白天睡眠增加.
结论:
- 干眼疾病与睡眠质量下降密切相关.
- 干眼患者面临睡眠障碍的风险增加,包括更长的入睡时间和不健康的睡眠模式.
- 研究结果强调了解决睡眠问题在干眼病管理中的重要性.
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