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在植入左心室辅助装置后,肺动脉脉动力和死亡率之间的关联

Ali Akamkam¹, Vincent Galand², Marie Jungling³

¹Department of Cardiovascular Surgery, Marie Lannelongue Hospital, Groupe Hospitalier Paris Saint Joseph, Le Plessis-Robinson, France.

ESC heart failure

|April 6, 2024

概括

手术前肺动脉脉动指数 (PAPi) 低于2.84表明左心室辅助装置 (LVAD) 植入后早期死亡风险更高. 然而,这不会影响在最初的时期生存的患者的长期存活率.

科学领域:

心脏病学心脏病学
医疗器械医疗器械
肺高血压是什么意思肺高血压

背景情况:

右心室衰竭是左心室辅助器件 (LVAD) 植入后的一个重大并发症.
预测这种并发症仍然是一个临床挑战.

研究的目的:

调查手术前肺动脉脉动指数 (PAPi) 与LVAD植入后死亡率之间的关联.
确定PAPI是否可以作为早期和长期结果的预测器.

主要方法:

对ASSIST-ICD多中心注册表的回顾性分析.
使用公式评估手术前PAPi: (静心肺动脉压 - 静心肺动脉压) / 中枢静脉压.
接收器操作特征 (ROC) 曲线分析以确定预测3个月生存的PAPI值.
多变量分析以确定2年死亡率的预测因素.

主要成果:

总共分析了117名患者 (平均年龄为58.45岁,15.4%是女性).
手术后右心室衰竭发生在48.7%的患者中.
确定了2.84的手术前PAPi值.
与PAPi<2.84 (58.1%) 相比,PAPi≥2.84的患者的3个月生存率 (89.1%) 显着更高.
在3个月后,没有观察到生存时间的显著差异.
系统性高血压,糖尿病和LVAD植入作为移植桥梁是2年死亡率的重要预测因素.

结论:

术前PAPi<2.84与LVAD植入后早期死亡风险增加有关.
这种早期风险似乎不会影响在最初的术后期生存的患者的2年生存结果.
在接受LVAD植入的患者中,PAPI可能是风险分层的一个有价值的工具.

关键词:

血液循环辅助装置可以帮助您的血液循环.数据库数据库数据库是一个数据库.血液动力学血液动力学心脏衰竭是因为心脏衰竭.左心室辅助装置的使用右心室,右心室.

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