牙周炎治疗对糖尿病高血糖的影响:一项前性队列研究
Brankica Davidović1, Jelena Krunić1, Irena Mladenović2
1Department of Dental Pathology, Faculty of Medicine Foca, University of East Sarajevo, Foca, Bosnia and Herzegovina.
International endodontic journal
|April 6, 2024
概括
在2型糖尿病患者 (T2DM) 中,根管治疗 (RCT) 的成功率较低,特别是在血糖不受控制的情况下 (HbA1c ≥7%). 然而,RCT可能会改善这些患者的血糖控制.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 糖尿病学 糖尿病学
- 在口腔外科手术.
背景情况:
- 2型糖尿病 (T2DM) 是一种影响愈合的全身性疾病.
- 通过HbA1c测量的血糖控制对于管理T2DM并发症至关重要.
- 根管治疗 (RCT) 旨在解决周周炎症和感染.
研究的目的:
- 为了评估不同血糖控制的T2DM患者的RCT成功率.
- 评估RCT对T2DM患者血糖控制的影响.
- 为了研究周周指数 (PAI) 评分和RCT后的血糖控制之间的关系.
主要方法:
- 前性队列研究,将T2DM患者 (目标HbA1c<7%和不受控制的HbA1c≥7%) 与对照组 (没有T2DM) 进行比较.
- 在RCT和12个月随访之前评估HbA1c和PAI得分.
- 统计分析包括集团间比较和回归分析.
主要成果:
- 通过减少放射性病变 (PAI分数) 表示的RCT成功率,在T2DM患者中不那么有利,特别是那些患有失控糖尿病 (UTL A1c) 患者.
- 与对照组相比,在RCT后12个月内,在UTL A1c组中愈合的牙显著减少 (PAI ≤2).
- 回归分析表明,在RCT (OR=4.788) 后,UTL A1c患者患上持续的顶端牙周炎 (AP) 的可能性更高.
- 相反,RCT显示了12个月后在UTL A1c患者中改善血糖控制的潜力.
结论:
- T2DM对RCT后的周周炎症愈合有负面影响,周周炎症可能会使血糖控制恶化.
- RCT可以降低T2DM患者的整体炎症负担.
- 改善T2DM患有失控糖尿病的患者的血糖控制可以提高RCT结果,并可能有利于整体代谢健康.
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