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一系列甲状腺细针吸收活检的病例被诊断为带有细胞特征的卵泡瘤
Constance V Chen1, Vimal Krishnan1, Nancy Y Greenland1
1Department of Pathology, University of California, San Francisco, San Francisco, California, USA.
Diagnostic cytopathology
|April 6, 2024
概括
细胞性甲状腺病变是一个诊断挑战. 这项研究回顾了三例瘤细胞毛囊瘤病例,这些病例是使用贝塞斯达甲状腺细胞病理报告系统 (TBSRTC) 诊断出来的,并通过分子检测得到确认.
科学领域:
- 内分泌学 在内分泌学.
- 手术病理学手术病理学
- 分子诊断学 分子诊断学
背景情况:
- 甲状腺的瘤细胞病变是多种多样的,包括良性和恶性类型.
- 传统的分类在甲状腺病理学中将这些实体分开.
- 准确的诊断对于患者管理至关重要.
研究的目的:
- 为了说明瘤细胞甲状腺病变的异质性.
- 为了介绍贝塞斯达的三种病例,第四类:毛囊瘤,细胞类型.
- 突出分子测试在诊断中的作用.
主要方法:
- 进行了细针吸收活检 (FNAB).
- 使用2017年贝塞斯达系统报告甲状腺细胞病理 (TBSRTC) 分析了细胞病理.
- 使用了ThyroSeq v3分子测试和外科切除.
主要成果:
- 确定了三例被诊断为贝塞斯达类别IV (毛囊性瘤,细胞类型) 的FNAB.
- 分子测试提供了额外的诊断信息.
- 手术切除证实了细胞病理学和分子发现.
结论:
- 瘤细胞毛囊瘤在甲状腺病理学中代表着一个重要的类别.
- 贝塞斯达甲状腺细胞病理报告系统 (TBSRTC) 对于初步诊断非常有价值.
- 分子测试,如ThyroSeq v3,有助于完善这些具有挑战性的病变的诊断和管理.
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