在治疗终身早泄时,注射球性肌肉博托克斯是否安全有效? 随机对照研究是随机对照研究
Hussein Shaher1,2, Karem Noah3, Mohamed Abdelzaher3
1Urology and Andrology Department, Faculty of Medicine, Benha University, Benha, Egypt. Hussein.shaher@fmed.bu.edu.eg.
World journal of urology
|April 6, 2024
概括
在bulbospongiosus肌肉中注射玻尿酸A毒素可以安全有效地治疗终身早泄 (PE). 这种治疗延长了阴道内射精潜伏时间,没有报告任何显著的并发症.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 安德罗学与人类学
- 药理学 药理学是指药理学的学科.
背景情况:
- 终身早泄 (PE) 是一种常见的性功能障碍.
- 现有的抗药性PE治疗方法存在局限性.
研究的目的:
- 评估注射肉毒素A毒素到bulbospongiosus肌肉中的安全性和有效性,用于终身耐药早泄 (PE).
主要方法:
- 98名终身PE患者被随机分配到肉毒素A或安慰剂组.
- 在超声波的指导下,注射了玻尿酸A毒素 (100U) 进入球肌.
- 阴道内射精潜伏时间 (IELT) 和性功能得分在1,3,6个月后进行评估.
主要成果:
- 与基线相比,素A毒素注射显著增加了IELT.
- 在早泄概况 (PEP) 评分中观察到改善.
- 在肉毒素A毒素组中没有报告任何显著的并发症;安慰剂没有显示任何效果.
结论:
- 毒素A毒素注射到球肌肉中是一种安全有效的PE治疗方法.
- 为了临床应用,需要进一步研究更大的样本大小和更长的随访时间.
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