带有神经调节呼吸辅助的全面罩作为重症支气管炎婴儿的救援疗法
Vladimir L Cousin1, Tiphaine Corbisier2, Peter C Rimensberger2
1Paediatric and Neonatal Intensive Care Unit, Department of Paediatrics, Gynecology and Obstetrics, University Hospital of Geneva, University of Geneva, Rue Gabrielle-Perret-Gentil 4, 1206, Geneva, Switzerland. Vladimir.cousin@hcuge.ch.
European journal of pediatrics
|April 6, 2024
概括
整体面膜非侵入性神经调节呼吸辅助 (TFM-NIV-NAVA) 为患有严重RSV支气管炎的婴儿提供可行的救援疗法,这些婴儿未能接受初始非侵入性通风 (NIV). 这种方法迅速改善了氧化,并避免了在小群体中输管治疗.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 呼吸系统生理学 呼吸系统生理学
- 机械通风机械通风机械通风
背景情况:
- 婴儿严重的支气管炎往往需要非侵入性通风 (NIV).
- 最初的NIV策略失败可能导致需要侵入性机械通风.
- 接口并发症可能会导致儿科患者的NIV失败.
研究的目的:
- 评估非侵入性神经调整呼吸辅助 (NIV-NAVA) 的可行性和有效性,使用全面罩 (TFM) 作为重症支气管炎和NIV衰竭的婴儿的救援疗法.
- 评估TFM-NIV-NAVA对氧化和通风参数的影响.
- 为了确定TFM-NIV-NAVA在这个患者群体中的耐受性和安全性.
主要方法:
- 对患有严重RSV支气管炎和初始NIV衰竭的婴儿 (0-6个月) 的回顾性研究.
- 患者被转换为TFM-NIV-NAVA作为救援治疗.
- 收集的数据包括人口统计,通风参数,氧化,二氧化碳水平和临床结果.
主要成果:
- 没有CPAP或NIV的10名婴儿接受了TFM-NIV-NAVA治疗.
- 在TFM-NIV-NAVA启动后1小时内,氧化显著改善.
- 没有患者需要输管,并且接口在不停止治疗的情况下被容忍得很好.
- 平均通风持续时间为2.5天,平均PICU停留时间为4.5天.
结论:
- TFM-NIV-NAVA似乎是一种可行且有效的救援疗法,用于患有严重RSV支气管炎的婴儿经历NIV失败.
- 这种方式可以快速改善恶化的婴儿的氧化.
- 对于选定的儿科患者来说,TFM-NIV-NAVA可能是一个有价值的选择,以潜在地避免侵入性通风.
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