人类免疫缺陷病毒 (HIV) 预防性疫苗的感知和接受:一种定性研究
Natalie V J Aldhouse1, Eric K H Chan2, Tamara Al-Zubeidi3
1Clinical Outcomes Assessment, Clarivate, London, UK. Natalie.Aldhouse@Clarivate.com.
The patient
|April 6, 2024
概括
预防性艾滋病毒疫苗被大多数成年人认为是有益的. 影响接受的关键因素包括感知到的风险,疫苗的安全性,有效性,成本和管理,风险组的接受率更高.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 定性研究是指质量研究.
背景情况:
- 尽管在预防艾滋病毒方面取得了进展,如PrEP,但新感染仍然很高,特别是在风险人群中.
- 预防性艾滋病毒疫苗可以减少疾病的流行和传播,克服与当前方法相关的坚持问题.
研究的目的:
- 探索美国一般,高风险和父母/照顾者群体对预防性艾滋病毒疫苗的看法和接受.
- 确定影响艾滋病毒疫苗接种的关键驱动因素和障碍.
主要方法:
- 定性研究涉及采访55个不同的成年参与者.
- 探索影响疫苗接受的个人,人际,社区,机构和结构因素.
- 开发一个概念模型,以了解疫苗接种率.
主要成果:
- 98%的参与者认为HIV疫苗是有益的.
- 关键考虑因素包括感知易感性,疫苗临床特征 (不良反应,疗效,成本,时间表) 以及对疫苗诱导的血清阳性方面的担忧.
- "风险"群体表现出最高的接受率 (70%);耻辱感不是一个重要的障碍.
结论:
- 了解人们对艾滋病毒疫苗安全性,有效性和管理的看法,对于制定有效的研究策略至关重要.
- 需要量身定制的公共卫生信息来支持未来的艾滋病毒疫苗接种计划,并提高接种率.
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