慢性鼻炎可能与慢性咳患者的肺功能下降有关
Pengfei Zhao1, Shin Kariya2, Takaya Higaki1
1Okayama University Academic Field of Medicine, Dentistry and Pharmaceutical Sciences, Department of Otolaryngology-Head and Neck Surgery, Okayama, Japan.
Brazilian journal of otorhinolaryngology
|April 6, 2024
概括
患有慢性咳 (CC) 的慢性鼻炎 (CRS) 患者的肺功能减弱,包括较低的FEV1.0和FEV1.0/FVC比率. 这些肺功能缺陷与CRS患者CT扫描严重性得分较高相关.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 肺部病理学 肺部病理学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 慢性咳 (CC) 显著影响生活质量.
- 慢性鼻炎 (CRS) 是一种常见的疾病,通常与持续的咳有关.
- CRS,CC和客观肺功能测量之间的关系需要进一步阐明.
研究的目的:
- 在被诊断为慢性鼻炎 (CRS) 和慢性咳 (CC) 的患者中调查肺功能参数.
- 探索肺功能,鼻腔疾病严重程度和免疫标志物之间的潜在相关性,在这个患者队列中.
主要方法:
- 对1413名CC患者的回顾性分析,包括109名CC患者的CRS患者.
- 评估肺功能 (FEV1.0,FEV1.0/FVC),隆德 - 麦凯CT得分,乙氨基酸细胞计数,IgE水平和中鼻结局测试 (SNOT).
- 包括一个正常的对照组进行比较分析.
主要成果:
- 与对照组相比,CRS和CC患者的FEV1.0,预测FEV1.0百分比和FEV1.0/FVC比率明显较低.
- 在患有严重鼻疾病的患者中,FEV1.0/FVC比率和隆德-麦凯CT得分之间观察到负相关性.
- 较高的CT得分与较差的肺功能结果有关.
结论:
- 肺功能评估对于患有慢性鼻炎和慢性咳的患者至关重要.
- 建议采用多学科的方法,包括咨询肺科医生,以最佳地管理患有CC的CRS患者.
- 识别客观肺功能缺陷可以帮助定制CRS相关咳的治疗策略.
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