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Updated: Jun 29, 2025

Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes
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Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes

Published on: June 3, 2018

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C166 EVs通过miR-148a-3p强化miR的心脏重编程

Hualing Sun1, Xinghua Wang2, Richard E Pratt2

  • 1Mandel Center for Heart and Vascular Research, and the Duke Cardiovascular Research Center, Duke University Medical Center, Durham, NC 27710, United States of America; Department of Periodontology, School and Hospital of Stomatology, Wuhan University, Hubei Province, China.

Journal of molecular and cellular cardiology
|April 6, 2024
PubMed
概括

研究人员开发了一种有效的方法,使用C166衍生的细胞外囊泡 (EV) 来输送用于心脏纤维细胞重编程的微RNA (miRNA) 组合. 这种方法在心肌梗塞模型中显著改善了心脏功能.

关键词:
一个心脏病患者的心脏病.电动汽车 (EV) 是一个纤维母细胞细胞是如何形成的副内的情况.重编程 重编程 是一种重编程.这就是miRNAs.

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Generation of Murine Cardiac Pacemaker Cell Aggregates Based on ES-Cell-Programming in Combination with Myh6-Promoter-Selection08:52

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