在重症监护病房幸存者的随访研究中保留参与者 - - 范围审查
Daniel L Young1, Awsse Al-Ani2, Mounika Lakhmalla3
1Department of Physical Therapy, University of Nevada, Las Vegas, Las Vegas, NV, USA; Outcomes After Critical Illness and Surgery Group, Johns Hopkins University, Baltimore, MD, USA; Department of Physical Medicine and Rehabilitation, School of Medicine, Johns Hopkins University, USA.
概括
参与者在重症监护室 (ICU) 生存研究中的保留率通常很高,但变化很大. 改进报告和研究设计对于准确的长期结果分析至关重要.
科学领域:
- 关键护理医学 关键护理医学
- 纵向研究的设计研究设计.
- 患者结局研究研究结果.
背景情况:
- 对于重症监护室 (ICU) 幸存者来说,医院后的结果至关重要.
- 参与者保留对于准确的长期结果评估至关重要.
- 目前关于这些研究中的保留报告不一致.
研究的目的:
- 在ICU幸存者的研究中综合参与者保留数据.
- 评估医院后结果研究中关于留住患者的报道.
- 确定影响参与者留守的因素,并建议改进.
主要方法:
- 使用PRISMA扩展范围审查检查清单进行系统的文献综合.
- 在多个数据库中进行了搜索 (PubMed,EMBASE,PsycINFO,CINAHL,Cochrane).
- 独立审稿人对文章和抽象数据进行了选,一致认为存在差异.
主要成果:
- 包括来自225项研究的243篇论文 (87,602名参与者).
- 在13%的研究和22%的随访时间点中无法计算保留时间.
- 保持率差异很大 (18%-100%),随访时间没有显著差异;最近的研究表明,保持率下降.
结论:
- 参与者保留率通常很高 (≥85%),但在很大一部分随访时间点中非常可变和不可计算.
- 需要改善关于报告保留方法的指导.
- 改进的研究设计和最佳实践可以提高保留率,保持统计能力并减少ICU幸存者研究中的偏见.
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