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乳腺损伤中的超声波粘度成像:一个多中心前性研究
WanRu Jia1, ShuJun Xia1, XiaoHong Jia2
1Department of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No.197 Ruijin 2nd Road, 200025 Shanghai, China; College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
超声波 (US) 粘度成像在与BI-RADS.相结合时可以提高乳腺病变的诊断. 这种新的方法提高了区分良性与恶性乳腺质量的准确性.
科学领域:
- 医疗成像医学成像
- 在瘤学瘤学.
- 诊断技术 诊断技术的使用
背景情况:
- 乳腺病变的特征依赖于成像和病理学.
- 像BI-RADS这样的当前方法在区分恶性和良性病变方面存在局限性.
- 超声波 (US) 粘度成像为评估组织特性提供了一种新的定量方法.
研究的目的:
- 评估美国粘度成像与BI-RADS联合用于乳腺损伤差异化的临床实用性.
- 为了比较联合美国粘度成像和BI-RADS与单独的BI-RADS的诊断性能.
- 通过开发和验证队伍验证发现.
主要方法:
- 一项前性多中心研究招募了639名患有乳腺病变的参与者.
- 组织学结果作为参考标准.
- 确定了与粘度相关的参数 (A'-S2-Vmax),并根据9.97 Pa.s.的切割值修改了BI-RADS.
主要成果:
- 最佳粘度参数A'-S2-Vmax在发育队列中显示AUC为0.88.
- 修改后的BI-RADS显著增加了所有队列的AUC,从0.85增加到0.90-0.91.
- 诊断性能的改善是统计学上显著的 (P < .05).
结论:
- 当与BI-RADS.集成时,美国定量粘度参数可以提高乳腺癌诊断的准确性.
- 美国粘度成像为乳腺病变的特征提供了有价值的补充信息.
- 这种技术有望改善非侵入性乳腺癌诊断.
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