相关实验视频
Updated: Jun 29, 2025

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
[幼儿脏病中脏病相关的口腔微生物的特征]
Jun Huang1, Xuan Han, Qi-Zhao Ma
1State Key Laboratory of Oral Diseases; National Clinical Research Center for Oral Diseases; Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University. Chengdu 610041, Sichuan Province, China.
在患有幼儿 (ECC) 的儿童中,口腔微生物多样性较低. 唾液和斑块中的特定细菌差异可能有助于ECC的预测和预防.
科学领域:
- 微生物学 微生物学
- 基因组学就是基因组学.
- 儿科牙科 儿科牙科
背景情况:
- 幼儿 (ECC) 是儿童口腔健康的一个重大问题.
- 了解口腔微生物组在ECC中的作用对于预防和治疗至关重要.
研究的目的:
- 通过使用16S rRNA高通量测序,研究口腔微生物在有和没有的儿童中的结构特征.
- 为了确定与早期儿童牙相关的特定微生物差异.
主要方法:
- 30名年龄在3-5岁的健康儿童被分为无虫 (CF) 和ECC组.
- 收集唾液和牙斑样本进行16S rRNA高通量测序.
- 生物信息学和统计分析 (SPSS 23.0) 用于比较微生物社区结构和多样性.
主要成果:
- 与CF组相比,ECC组的微生物多样性明显低于CF组.
- 行为细菌在ECC组的唾液中更为丰富,而Firmicutes在CF组的斑块中更为丰富.
- 像Rothia和Corynebacterium这样的特定品种与ECC组相关,而Lautropia, Cardiobacterium,Gemella和Granulicatella与CF组相关.
结论:
- 在患有牙和没有牙的儿童之间,口腔微生物群落的组成存在显著差异.
- 某些微生物与ECC的发展有关.
- 识别这些特定的微生物可以帮助早期预测和预防ECC.
更多相关视频
08:20Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
09:44Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
Published on: October 20, 2011
相关概念视频
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
Psychosexual Stages of Personality: Oral
Weaning, typically occurring...
Oral Cavity
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...