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在急诊室最近接种疫苗的发烧婴儿中存在严重的细菌感染风险
Kyla Casey1, Erin R Reilly1, Katherine Biggs2
1Department of Emergency Medicine, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA 92134, United States of America.
The American journal of emergency medicine
|April 7, 2024
概括
最近接种免疫 (RI) 的6-12周的婴儿发烧具有严重细菌感染 (SBI) 的低风险,特别是侵入性细菌感染. 尿路感染仍然是一个问题,需要进行尿液分析和培养.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 临床实践指南 临床实践指南
背景情况:
- 在免疫接种后,发烧是婴儿常见的担忧.
- 目前的临床指导方针不包括最近免疫接种 (RI) 的婴儿,这给管理带来了挑战.
- 评估发烧RI婴儿严重细菌感染 (SBI) 患病率至关重要.
研究的目的:
- 为了确定SBI在最近免疫 (RI) 发烧的婴儿6至12周的流行率.
- 为了比较RI婴儿中的SBI率与最近没有免疫接种 (NRI) 的婴儿.
主要方法:
- 在两个军事学术EDS中,对发烧婴儿 (6-12周) 的回顾性图表审查.
- 婴儿被归类为RI (72小时内免疫) 或NRI.
- 主要结局:SBI的流行 (侵入性细菌感染[IBI]和非侵入性细菌感染[非IBI]).
主要成果:
- 整体SBI患病率为11.4%.
- 与NRI婴儿 (13.7%) 相比,RI婴儿的SBI患病率较低 (3.5%).
- 在RI婴儿中SBI的相对风险为0.3;在RI婴儿中没有观察到IBI病例,大多数SBI是尿路感染.
结论:
- 最近接种免疫 (6-12周) 的婴儿患入侵性细菌感染 (IBI) 的风险很低.
- 在免疫接种后24小时内,RI婴儿的非侵入性细菌感染显著降低.
- 尿路感染 (UTI) 是RI婴儿的风险;建议进行尿液分析和培养,以支持共同决策,以减少侵入性护理.
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