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基于细胞外囊泡的基因疗法,用于治疗光盘性背痛

Shirley N Tang1, Ana I Salazar-Puerta1, Mary K Heimann1

  • 1Department of Biomedical Engineering, College of Engineering, The Ohio State University, USA.

Biomaterials
|April 7, 2024
PubMed
概括

这项研究引入了一种新型的基因疗法,用于使用工程外细胞囊泡传递FOXF1.1.的迪斯科原性背痛. 在动物模型中,治疗成功地减少了疼痛,并恢复了椎间盘结构和功能.

关键词:
细胞重编程可以进行.工程设计的细胞外囊泡.椎间盘之间的椎间盘.腰部疼痛 腰部疼痛 腰部疼痛纳米载体的使用方法非病毒基因传递非病毒基因传递

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