预先存在的心力衰竭和癌症发病率之间的关联:系统性审查和元分析
Carla Barbosa1, André Cabrita2, Camila Dias3
1Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
概括
心力衰竭 (HF) 与患癌症和经历癌症相关死亡的风险更高有关. 这包括肺癌,胃肠道癌,血液癌和女性生殖系统癌症的风险增加.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 和癌症是全球主要的死亡原因.
- 癌症是心力衰竭 (HF) 患者死亡的重要原因.
- 新出现的证据表明HF与癌症的发展或进展之间存在潜在联系.
研究的目的:
- 系统地审查和分析有关心力衰竭和癌症发展之间的联系的现有证据.
- 讨论HF与癌症发病率和死亡率之间的关系.
主要方法:
- 在PubMed,Web of Science和ClinicalTrials.gov进行了全面的文献搜索,截至2022年11月.
- 包括的研究集中在患有HF的患者和随后的癌症诊断,报告发病率或死亡率结果.
- 对报告危险比率 (HR) 或相对风险的研究进行了元分析.
主要成果:
- 对13项研究的分析显示,高频率与30%的整体癌症发病率增加有关 (HR=1.30).
- 亚组分析表明肺癌 (HR=1.87),胃肠癌 (HR=1.22),血液癌 (HR=1.60) 和女性生殖系统癌 (HR=1.67) 的风险增加.
- 在HF患者中,与癌症相关的死亡率明显高 (HR=2.17).
结论:
- 心力衰竭可能是癌症发病率和死亡率的先兆,并增加癌症发病率和死亡率的风险.
- 肺癌,女性生殖和血液癌是HF患者中观察到的最常见的亚型.
- 进一步的研究对于阐明这种关联和优化患者护理至关重要.
关键词:
癌症 癌症 癌症 癌症这就是Cancro Cancro.心脏瘤学是一门学科.心脏瘤学 - 心脏瘤学心脏衰竭是因为心脏衰竭.事件发生率 事件发生率发生的事件 Incidência没有心脏衰竭.死亡率 死亡率 死亡率死亡率 死亡率 死亡率更多相关视频
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