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Updated: Jun 29, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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通过使用VariPred的蛋白质语言模型增强误解变体病原性预测

Weining Lin1, Jude Wells2, Zeyuan Wang3

  • 1Division of Biosciences, Institute of Structural and Molecular Biology, University College London, London, UK.

Scientific reports
|April 7, 2024
PubMed
概括

VariPred是一种新的计算工具,使用蛋白质序列准确预测遗传变异的病原性. 这种方法通过利用先进的蛋白质语言模型而优于现有方法,而不需要复杂的特征工程.

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