在具有高反应性侵略性的青少年中,边缘网络的皮层体积变化
Johannah Bashford-Largo1,2, R James R Blair3, Karina S Blair1
1Child and Family Translational Research Center, Boys Town National Research Hospital, Boys Town, NE, USA.
Development and psychopathology
|April 7, 2024
概括
具有更高反应性侵略性的青少年在右边边缘网络和极中显示出更大的皮质体积. 这项研究突出了与年轻人攻击性亚型相关的特定大脑网络.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 精神病学是一个精神病学.
背景情况:
- 之前的研究表明,与侵略相关的前额和边缘区域的结构性大脑变化.
- 有限的研究已经探索了攻击性亚型及其神经网络相关的,更多地关注整体攻击性和特定区域.
研究的目的:
- 确定与青少年反应性和主动性侵略亚型相关的特定大脑网络和区域.
- 调查与侵略亚型相关的皮质体积的结构差异.
主要方法:
- 分析了340名青少年 (平均年龄16.29岁) 的结构性MRI数据.
- 使用反应性积极性攻击问卷 (RPQ) 评估了侵略症状.
- 使用Freesurfer在七个网络中估计皮层体积 (CV),在低与高侵略群体进行MANCOVA.
主要成果:
- 在七个反应性侵略网络中发现了CV的显著主效应 (p = 0.022).
- 具有更高反应性侵略性的青少年在右边边缘网络 (p = 0.029) 和极 (p = 0.011) 中表现出显著更大的皮质体积.
- 在提供的摘要中,针对主动侵略没有报告任何显著的结果.
结论:
- 研究结果表明,右边缘网络和极都与反应性攻击有关.
- 这些区域皮质体积增加可能是青少年反应性侵略的结构相关因子.
- 这些结果与先前的研究相一致,该研究将边缘网络和极与反应性侵略调节和启动联系起来.
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