FIGL1 防止异常染色体结合和碎片化,并限制多倍体小麦化中的交叉
Kim Osman1, Stuart D Desjardins2, James Simmonds3
1School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
The New phytologist
|April 8, 2024
概括
破坏小麦中的FIGL1基因会增加介质交叉 (COs),增强遗传多样性. 虽然四形突变体是无菌的,但六形突变体表现出中度的生育能力,这表明小麦繁殖的潜力.
科学领域:
- 植物遗传学 植物遗传学
- 分子生物学分子生物学
- 农作物科学 农作物科学
背景情况:
- 介质交叉 (COs) 对于植物的遗传多样性和可活性性交配体的产生至关重要.
- 小麦表现出有限的COs (每对1-3),偏偏偏,阻碍了作物改善.
- 小麦基因组学的进步为研究和修改重组提供了新的途径.
研究的目的:
- 调查FIGL1基因的破坏,作为修改小麦中CO频率和位置的策略.
- 分析FIGL1干扰在四和六小麦中的影响.
主要方法:
- 使用细胞遗传学分析figl1突变物和病毒诱导的基因沉默线.
- 在六倍体小麦中进行遗传映射.
- 量化COs和喘频率的量化.
- 对HEI10焦点数量的分析.
主要成果:
- 在四平状小麦中,FIGL1的干扰抑制了II类COs,在一个四倍突变的figl1 msh5中,CO/喘频率增加了2.1倍.
- 在基于HEI10焦点的六倍状小麦中,FIGL1似乎没有影响I类COs.
- 基因映射显示,尽管整体没有增加,但在六倍体图1突变体中,特定间隔增加了重组.
- 四体突变动物是无菌的,但六体突变动物表现出中度的生育能力.
结论:
- 在小麦中,FIGL1在抑制II类介质交叉中发挥作用.
- 破坏FIGL1可以增加重组频率并改变其分布,这可能对小麦育种产生潜在影响.
- 六倍体图1突变的中等生育率表明,它们在改善小麦品种方面具有潜在的效用.
关键词:
这就是Triticum.在FIGL1中,FIGL1是FIGL1的前身.染色体是一种染色体.遗传交叉发生在基因上.介质变化 (meiosis) 是一种变质的过程.多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种多种再组合的复合方式.小麦小麦小麦小麦小麦小麦小麦.相关概念视频
Meiosis II
45.6K
Meiosis II entails cell division and segregation of the sister chromatids, resulting in the production of four unique haploid gametes. The steps for meiosis II are similar to mitosis, except that meiosis II occurs in haploid cells, whereas mitosis occurs in diploid cells.
The timing and cell division patterns of meiosis differ between males and females. In male meiosis, the centrosomes are part of the formation of the meiotic spindle. However, in oocytes, including that of humans, Drosophila,...
The timing and cell division patterns of meiosis differ between males and females. In male meiosis, the centrosomes are part of the formation of the meiotic spindle. However, in oocytes, including that of humans, Drosophila,...
45.6K
Meiosis I
40.6K
Meiosis is the division of a diploid cell into haploid cells forming sperm and eggs in animals through differentiation. Meiosis I is the first stage of meiosis, where the genetic recombination of homologous chromosomes and the reduction of the ploidy level by half occurs.
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
40.6K
The Spindle Assembly Checkpoint
3.2K
The spindle assembly checkpoint is a molecular surveillance mechanism ensuring the fidelity of chromosome segregation during anaphase. The checkpoint monitors the completion of all the prerequisite steps before chromosome segregation to determine whether the segregation process should proceed or be delayed.
Many proteins function together to control the spindle assembly checkpoint. Mutations affecting these proteins may allow cells to proceed into anaphase prematurely, resulting in the...
Many proteins function together to control the spindle assembly checkpoint. Mutations affecting these proteins may allow cells to proceed into anaphase prematurely, resulting in the...
3.2K
Crossing Over
146.8K
Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process...
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process...
146.8K
Separation of Sister Chromatids
3.6K
At the transition from prophase to metaphase, there is a reduction in cohesion along the chromosomal arms, resulting in the resolution of sister chromatids. However, residual cohesin connections remain to hold the sister chromatids together until the transition from metaphase to anaphase. The residual connection prevents any premature separation of sister chromatids, blocking the risks of aneuploidy within the daughter cells.
At the onset of anaphase, separase, a proteolytic enzyme, is...
At the onset of anaphase, separase, a proteolytic enzyme, is...
3.6K
Cohesins
4.5K
Cohesin protein complexes are a molecular glue that holds two sister chromatids together. They play an important role both in mitosis and meiosis. In mitosis, all cohesin complexes present on the chromosomes are removed before the start of the anaphase stage.
Cohesin complexes in Meiotic Division
Meiosis involves two distinct rounds of chromosomal segregation and cell divisions— Meiosis I followed by Meiosis II – producing four daughter cells. Meiosis I includes the separation of...
Cohesin complexes in Meiotic Division
Meiosis involves two distinct rounds of chromosomal segregation and cell divisions— Meiosis I followed by Meiosis II – producing four daughter cells. Meiosis I includes the separation of...
4.5K


