与健康对照人群相比,患有全身性硬化症的男性的性功能和骨盆底功能:一个横截面研究
Barbora Heřmánková1,2, Sabína Oreská1,3, Maja Špiritović1,2
1Institute of Rheumatology, Prague, Czech Republic.
概括
与健康人相比,患有全身性硬化症 (SSc) 的男性发生性功能障碍 (SD) 和勃起障碍 (ED) 的比率明显更高. 盆地功能似乎不是SSc患者SD的促成因素.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 类风湿病学 类风湿病学
- 性医学性医学性医学性医学
背景情况:
- 系统性硬化症 (SSc) 是一种复杂的自身免疫性疾病,影响多个器官系统.
- 性功能 (SF) 和盆地功能 (PF) 是生活质量的重要方面,可能会受到慢性疾病的影响.
研究的目的:
- 为了比较男性的性功能和骨盆底功能,SSc与年龄相匹配的健康对照 (HC) 相比.
- 确定与男性性功能受损相关的临床因素.
主要方法:
- 一项涉及20名SSc和20名HC的男性 (年龄18-70岁) 的横截面研究.
- 使用国际勃起功能指数 (IIEF) 和男性性健康问卷 (MSHQ) 评估SF.
- 评估盆地功能,使用盆地影响问卷-简短表格7 (PFIQ-7),以及关于疲劳,抑郁和生活质量的问卷.
主要成果:
- 患有SSc的男性报告了显著更糟糕的SF,70%的人经历勃起功能障碍 (ED),而HC的15% (p < 0.001).
- 在SSc患者和HC患者 (p = 0.141) 之间,没有发现骨盆底功能的显著差异.
- 在SSc中受损的SF与更高的疾病活动,炎症,疲劳,身体健康降低,抑郁和更差的生活质量有关.
结论:
- 性功能障碍在患有系统性硬化症的男性中非常普遍.
- 在这个人群中,盆地功能障碍不太可能是性功能障碍的主要原因.
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