用COVID-19患者血清进行蛋白质组研究的研究趋势:图书法测量分析
Érika Alves da Fonsêca Amorim1, Roberval Nascimento Moraes Neto2, Ana Viviam Souza1
1Programa de Pós-graduação em Odontologia, Universidade CEUMA, 65075-120, São Luís, MA, Brazil.
Current medicinal chemistry
|April 8, 2024
概括
血清蛋白质学为疾病管理提供了新的COVID-19生物标志物. 本文献分析突出了关键蛋白质和研究趋势,有助于未来的冠状病毒病2019的诊断和治疗策略.
科学领域:
- * 生物医学研究和诊断
- * 蛋白质组学和生物标记物的发现.
- * 传染病流行病学
背景情况:
- *COVID-19大流行导致了广泛的死亡率,需要改进疾病管理策略.
- *血清蛋白质学为识别与COVID-19相关的分子变化提供了一种有价值的方法.
- *确定可靠的生物标志物对于有效的患者护理和治疗至关重要.
研究的目的:
- *对与COVID-19相关的血清蛋白质学研究进行文献计量评估.
- *分析当前的研究状况,并确定该领域的新兴趋势.
- *从2020年到2023年绘制COVID-19血清蛋白质组学研究的地图.
主要方法:
- *对科学文献进行图书法分析.
- *数据来源于科学网络和Scopus数据库.
- *使用VOSviewer软件进行的分析,用于关键字并发和趋势识别.
主要成果:
- *分析了2020年1月至2023年2月间发表的48篇文章.
- *中国和美国被确定为COVID-19血清蛋白质组学研究的领先国家.
- *关键的研究主题包括生物标记物识别,诊断和治疗,其中经常引用的蛋白质包括IgG,IgM,互白蛋白,SAA1和ApoA-1.
结论:
- *血清蛋白质组学是了解COVID-19分子基础的重要工具.
- *已识别的生物标志物显示出改善COVID-19患者管理和治疗策略的潜力.
- * 本文献统计概述指导未来对SARS-CoV-2和宿主免疫相互作用的研究.
更多相关视频
08:21Cell-Free Dot Blot as a Practical and Adaptable Immunoassay Platform for the Detection of Antibody Response in Human and Animal Sera
Published on: May 23, 2025
216
05:30Author Spotlight: Advancing the Analysis of Plasma Extracellular Vesicle Proteome for Cardiovascular Biomarker Studies
Published on: January 31, 2025
387
相关概念视频
01:33Proteomics
7.3K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.3K
02:50Conjugated Proteins
18.3K
Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
18.3K