氧化形成的酸盐还原酶的遗传学和环境分布揭示了它们独特的功能和生态作用
Grace Pold1, Germán Bonilla-Rosso1, Aurélien Saghaï1
1Department of Forest Mycology and Plant Pathology, Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden.
ISME communications
|April 8, 2024
概括
酸盐还原酶NirK和NirS具有不同的生态作用,它们的进化历史反映了生物生态. 它们的分布在各种环境中各不相同,影响着元素循环.
科学领域:
- 微生物生态学 微生物生态学
- 生物地质化学生物地质化学
- 进化生物学 进化生物学
背景情况:
- 酸盐还原酶NirK和NirS是循环中的关键酶,在脱过程中经常表现出冗余的功能.
- 这些酶存在于各种生物体中,包括那些不进行脱的生物体,这表明它们具有更广泛的生态作用.
- 在NirK和NirS血统中存在显著的序列和结构变异.
研究的目的:
- 阐明NirK和NirS酶的功能作用和生态.
- 分析NirK和NirS蛋白家族中的序列和结构变异.
- 为区分编码不同酸盐还原酶系的有机体的生态作用建立基因组学框架.
主要方法:
- 用6973个隔离基因组和元基因组组合基因组的序列来重建NirK和NirS的强大的基因组.
- 识别了32个结构上不同的蛋白质系的良好支持的分类.
- 通过分析相关的功能基因和4082个环境元基因组中的相对丰度来推断类型特定的生态.
主要成果:
- 尼尔K和尼尔S族系明显地回顾了生物生态,揭示了类特定的环境分布和利基偏好.
- 化剂构成了化物减少社区的重要组成部分,特别是在海水和干燥土壤中的Nirk.
- 尼尔S和尼尔K与其他元素循环中涉及的基因的明显关联表明它们与不同的生物地球化学过程的联系,在生物体中丰富和多样性各不相同.
结论:
- 尼尔K和尼尔S酶发挥着不同的生态作用,影响各种元素循环,超出了脱.
- 开发的遗传学框架允许区分与编码不同的酸盐还原酶系的有机体相关的特征.
- 了解这些不同的角色对于理解各种生态系统中的微生物社区功能至关重要.
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