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确定在EUS-FNB期间诊断胰腺固体病变的最佳通行次数:前性多中心研究

Benedetto Mangiavillano¹, Antonio Facciorusso², Francesco Maria Di Matteo³

¹Gastrointestinal Endoscopy, Istituto Clinico Mater Domini Casa di Cura Privata SpA, Castellanza, Italy.

Endoscopy international open

|April 8, 2024

概括

在内镜超声波引导细针活检 (EUS-FNB) 中进行两次针刺,可显著提高固体胰腺病变的诊断准确度. 第三次通过不会进一步提高结果,表明两次通过对于准确的EUS-FNB诊断是最佳的.

科学领域:

胃肠病学胃肠病学
干预性内镜检查是干预性的内镜检查.
在瘤学瘤学.

背景情况:

在胰腺病变的内镜超声波引导细针活检 (EUS-FNB) 中,最佳的针通过仍未确定.
EUS-FNB是固体胰腺病变的关键诊断工具.

研究的目的:

为了评估 EUS-FNB 对固体胰腺病变的连续注射针的诊断准确性.
为了确定达到诊断准确性的最佳针刺次数.

主要方法:

这项前性研究涉及11个意大利中心的168名患有固体胰腺病变的患者.
进行了三次连续的针刺,进行了个体样本处理和宏观现场评估 (MOSE).
评估了诊断准确性,敏感性,样本充分性,MOSE可靠性和不良事件.

主要成果:

诊断准确度从一次通过后的90.5%显著增加到两次通过后的97.6% (P=0.01).
诊断灵敏度和样本充分性也显著改善,两次通过与一次相比.
精度,灵敏度和充分性在第三次通过后停滞不前;MOSE一致性为89.9%.

结论:

通过EUS-FNB建议至少进行两次针刺,以通过EUS-FNB准确诊断固体胰腺病变.
现场宏观评估 (MOSE) 是预测组织学样本充分性的可靠方法.

关键词:

内镜超声波检查 (Endoscopic ultrasonography) 是一种内镜超声波检查,用于检查内镜超声波.精细针吸收/活检可以进行.胰腺是什么? 胰腺是什么?

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