来自Mentha的纳米战士:使用氧化纳米粒子释放大自然的抗菌武器库
Maarij Khan1, Rahmat Wali1, Zia-Ur-Rehman Mashwani1,2
1Department of Botany, Pir Mehr Ali Shah (PMAS)-Arid Agriculture University, Rawalpindi 46000, Pakistan.
ACS omega
|April 8, 2024
概括
基于药用植物的氧化纳米颗粒 (CeO2NP) 显示出强大的抗微生物和抗真菌特性. 这些绿色合成的CeO2NP,与薄荷叶提取物稳定,由于其低毒性和有效性,为制药和食品防腐剂应用提供了潜力.
科学领域:
- 纳米技术纳米技术
- 材料科学 材料科学 材料科学
- 微生物学 微生物学
背景情况:
- 氧化纳米颗粒 (CeO2NP) 由于其带正电的表面,表现出抗菌活性,促进病原体细胞膜破坏和纳米颗粒进入.
- 来自药用植物的植物化学物质可以通过表面功能化来增强CeO2NP的治疗潜力.
- 绿色合成为纳米粒子生产提供了一种可持续的方法,具有增强生物活性的潜力.
研究的目的:
- 用薄荷叶提取物合成和表征植物化学涂层CeO2NP.
- 为了评估这些绿色合成的CeO2NP对各种病原细菌和真菌的抗微生物和抗真菌功效.
- 调查植物源和纳米粒子特征对抗微生物活性的影响.
主要方法:
- 使用 *Mentha royleana*, *Mentha longifolia* 和 *Mentha arvensis* 的叶子提取物进行CeO2NP的绿色合成.
- 描述CeO2NP的特征,重点关注尺寸变化和面积比.
- 对抗 * 黄金葡萄球菌*, * 斑点球菌表皮菌*, * Escherichia coli*, * 菌菌 (Stenotrophomonas maltophilia), * 菌菌 (Comamonas sp.), * 菌菌 (Halobacterium sp.), * 肺炎菌 (Klebsiella pneumoniae) 和 * 菌菌菌 (Xanthomonas sp.) 的抗菌活性进行评估.
- 使用条纹板方法对*Bipolaris sorokiniana*,*Aspergillus flavus*和*Fusarium oxysporum*的抗真菌活性进行评估.
主要成果:
- 用薄荷提取物对CeO2NP进行植物化学涂层,显著增强了它们的抗微生物和抗真菌特性.
- 合成的CeO2NP显示出对所有测试的致病性细菌和真菌具有良好至优良的抑制活性.
- 纳米颗粒大小和表面与体积比的变化,受使用的特定Mentha物种的影响,与抗菌效率相关.
结论:
- 绿色合成,植物化学涂层的CeO2NP具有显著的抗菌和抗真菌特性.
- 该研究强调了基于Mentha物种的CeO2NP在制药应用和作为天然食品防腐剂的潜力.
- 植物来源,纳米粒子大小和表面特性等因素对于优化绿色CeO2NP的抗菌潜力至关重要.
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