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相关概念视频

Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

9.2K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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Olfaction01:25

Olfaction

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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
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Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

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Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
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Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
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Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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相关实验视频

Updated: Jun 29, 2025

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
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Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

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在糖尿病中嗅觉功能.

Beata Sienkiewicz-Oleszkiewicz1,2, Thomas Hummel2

  • 1Department of Clinical Pharmacology, Faculty of Pharmacy, Wroclaw Medical University, ul. Borowska 211a, 50-556 Wrocław, Poland.

Journal of clinical & translational endocrinology
|April 8, 2024
PubMed
概括
此摘要是机器生成的。

糖尿病 (DM) 与嗅觉障碍的更高风险有关,特别是当与肥胖或COVID-19等疾病相结合时. 需要进一步的研究来了解糖尿病患者的嗅觉丧失.

关键词:
在 COVID-19 疫情中,糖尿病是一种糖尿病.肥胖问题 肥胖问题嗅觉是一种嗅觉.甲状腺功能 甲状腺功能

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Olfactory Assays for Mouse Models of Neurodegenerative Disease
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Olfactory Assays for Mouse Models of Neurodegenerative Disease

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A Free-breathing fMRI Method to Study Human Olfactory Function
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A Free-breathing fMRI Method to Study Human Olfactory Function

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相关实验视频

Last Updated: Jun 29, 2025

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

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Olfactory Assays for Mouse Models of Neurodegenerative Disease
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A Free-breathing fMRI Method to Study Human Olfactory Function
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A Free-breathing fMRI Method to Study Human Olfactory Function

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科学领域:

  • 内分泌学 在内分泌学.
  • 神经学 神经学
  • 耳鼻喉科 耳鼻喉科 耳鼻喉科

背景情况:

  • 糖尿病 (DM) 是一种普遍的疾病,影响儿童和成人.
  • 糖尿病可能导致神经和血管问题,包括化学感官缺陷,如嗅觉恶化.
  • 嗅觉功能障碍越来越被认为是糖尿病的并发症.

研究的目的:

  • 综合有关糖尿病患者嗅觉功能的当前知识.
  • 检查伴随性疾病 (肥胖,甲状腺功能障碍,CKD,COVID-19) 对DM的嗅觉结果的影响.
  • 突出进一步研究的必要性和DM嗅觉下降的实际影响.

主要方法:

  • 文献综述和综合有关糖尿病嗅觉功能的现有研究.
  • 分析研究研究共患病对DM中嗅觉障碍的影响.
  • 确定当前研究的局限性,包括研究规模和方法.

主要成果:

  • 嗅觉障碍在糖尿病患者中比一般人群更为普遍.
  • 肥胖,甲状腺功能障碍,慢性病和COVID-19等并发症加剧了DM的嗅觉衰退.
  • 嗅觉功能障碍在1型,2型和妊娠期糖尿病中观察到,以及在急性DM相关的疾病中,如COVID-19.

结论:

  • 嗅觉的恶化是糖尿病的一个重要问题,常常因同时存在的健康状况而恶化.
  • 目前的研究存在局限性,需要进行更大规模的标准化研究,以澄清DM,并发病症和嗅觉功能之间的关系.
  • 嗅觉能力下降可能是糖尿病患者神经问题,营养状况,认知功能和甲状腺异常的早期指标.