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中枢静脉狭窄症在黑白ESKD患者中的患病率功能障碍透析接入患者

Nkiruka Arinze¹, Jonathan D Ravid², Kristina Yamkovoy³

¹Division of Vascular and Endovascular Surgery, Boston Medical Center, Boston University School of Medicine, Boston, MA 02118, USA.

Journal of health disparities research and practice

|April 8, 2024

概括

研究了最终阶段病 (ESKD) 管理中的种族差异. 虽然中枢静脉狭窄症 (CVS) 的患病率在黑人和白人患者之间相似,但白人患者的狭窄症更严重,糖尿病与静脉疾病有关.

科学领域:

腎臟病學 (nephrology) 是一種醫學專業.
血管外科血管外科
公共卫生公共卫生

背景情况:

在美国,慢性病 (CKD) 和末期病 (ESKD) 管理方面存在显著的种族和民族差异.
血液透析是一种主要的置换疗法,通常是通过中央静脉导管 (CVC) 开始的.
黑人患者的CVC使用和持续时间更高,可能会增加诸如中枢静脉狭窄 (CVS) 等并发症的风险.

研究的目的:

调查中枢静脉狭窄 (CVS) 的患病率和风险,黑人与白人的末期病 (ESKD) 患者.
为了确定种族是否影响CVS的严重程度.
在ESKD患者中识别与CVS相关的风险因素.

主要方法:

对428名ESKD患者的回顾性审查,这些患者因透析接入功能故障而接受了fistulogram.
中枢静脉狭窄症 (CVS) 定义为中枢静脉中>50%的狭窄症.
分析了370个自报告的黑白ESKD患者的fistulograms.

主要成果:

在黑人 (40%) 和白人 (41%) ESKD 患者之间,CVS 患病率没有显著差异.
白人ESKD患者表现出更严重的狭窄 (>70%) (P=0.03).
在风险调整模型中,糖尿病与心血管系统显著相关;在未调整模型中,心血管疾病和心血管系统使用与心血管系统相关.

结论:

这项研究发现CVS患病率没有差异,但白色ESKD患者的严重程度更高.
糖尿病被确定为ESKD中狭窄静脉疾病的危险因素.
需要使用更大的数据集进行进一步的研究,以探索种族和种族对CVS的影响.

关键词:

在CKD中,它是最好的.在 ESKD 的意思是 ESKD 中枢静脉狭窄症的发生.血液透析是血液透析的方法之一.

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