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Updated: Apr 8, 2026

Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells
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通过使用倒置的frustoconical震动生物反应器,提高基于抗体的生物治疗产品的产品质量和生产率

Xuekun Wang1,2, Jin Xu1,2,3, Qingcheng Guo1,2,3,4

  • 1State Key Laboratory of Macromolecular Drugs and Large-scale Manufacturing, School of Pharmaceutical Sciences, Liaocheng University, Liaocheng, China.

Frontiers in bioengineering and biotechnology
|April 8, 2024
PubMed
概括

与传统的式生物反应器 (STR) 相比,反转式动生物反应器 (IFSB) 为抗体生产提供了增强的生物过程性能和产品质量. IFSB技术提高了细胞活力和蛋白质表达,使其成为生物制药制造的有希望的替代品.

关键词:
基于抗体的生物治疗方法.倒置的冷式摇动生物反应器生产力生产力生产率的提高.扩大规模的生产生产.的生物反应器被起来.

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Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation09:28

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