医院中的3D打印机:常见的细菌污染和抗菌3D打印材料的细菌污染
Katelin C Jackson1, Erin Clancey1, Douglas R Call1
1Paul G. Allen School for Global Health; Washington State University, Pullman, WA, USA.
bioRxiv : the preprint server for biology
|April 8, 2024
概括
3D打印的医院材料,包括抗菌丝,很容易被污染,可以维持细菌的生长. 虽然消毒减少了污染,但细菌种群可以恢复,这凸显了适当的材料选择和清洁协议的必要性.
科学领域:
- 微生物学 微生物学
- 材料科学 材料科学 材料科学
- 医疗保健工程 医疗保健工程
背景情况:
- 在COVID-19等危机期间,医院面临个人防护设备 (PPE) 短缺问题.
- 自产的个人防护设备,包括3D打印的物品,越来越多地用于弥补供应缺口.
- 3D打印材料在医疗机构的消毒效果和抗菌性质尚不清楚.
研究的目的:
- 评估3D打印材料的污染潜力和消毒效率,包括标准PLA和抗菌纤维 (PLACTIVE,BIOGUARD).
- 为了确定抗微生物纤维是否有效地减少细菌污染与标准PLA相比,在各种条件下.
- 评估消毒效率的变化和3D打印材料消毒后细菌再生的可能性.
主要方法:
- 在不同条件下 (例如,层高度,接触时间) 在用PLA,PLACTIVE和BIOGUARD制成的3D打印磁盘上进行了细菌污染测试.
- 在受污染的磁盘上测试了消毒效果,随后随着时间的推移对细菌恢复进行了监测.
- 殖民地形成单位 (CFU) 计数被用来量化消毒前后的细菌水平.
主要成果:
- 发现包括PLACTIVE和BIOGUARD在内的3D打印材料容易被常见的医院细菌和持续污染污染.
- 根据特定的打印参数和细菌接触时间,PLACTIVE和BIOGUARD的污染水平各不相同,有时超过或低于PLA.
- 虽然消毒减少了CFU的数量,但它的有效性是可变的,细菌群体在消毒后显示恢复时间.
结论:
- 适当的消毒和仔细选择3D打印材料对于减轻医院中的细菌污染风险至关重要.
- 抗微生物3D打印材料需要环境服务部门的意识,因为潜在的污染和再生.
- 为了保持安全标准,建议在医院中不鼓励患者打印的物品.
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