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Updated: Jun 29, 2025

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在阿尔茨海默病小鼠模型中,AIBP控制TLR4炎症和线粒体功能障碍

Yi Sak Kim1, Soo-Ho Choi1, Keun-Young Kim2

  • 1Department of Medicine, University of California, San Diego, La Jolla, CA, 92093, USA.

bioRxiv : the preprint server for biology
|April 8, 2024
PubMed
概括

ApoA-I结合蛋白 (AIBP) 通过调节微质炎症反应和线粒体功能来保护阿尔茨海默病. 删除AIBP会在小鼠模型中恶化神经炎症,氧化应激和神经退行.

关键词:
一个AIBPP的AIBP.阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.在 TLR4 中,炎症的左翼是炎症的脂质漂浮艇是什么意思 脂质漂浮艇是什么意思微质细胞中的微质细胞线粒体中的线粒体.神经炎症是一种神经炎症.氧化应激是一种氧化应激.

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