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Updated: Jun 27, 2026

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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结质瘤DNA甲基化分析:分析前变量的评估

Karol Bomsztyk, Daniel Mar, Oleg Denisenko

    bioRxiv : the preprint server for biology
    |April 8, 2024
    PubMed
    概括

    样本存储和处理等分析前变量不会显著影响O6-甲基瓜因-DNA甲基转移酶 (MGMT) 促进剂甲基化分析. 然而,瘤内异质性需要多次活检以进行准确的MGMT甲基化评估.

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    Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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