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Updated: Jul 23, 2026

Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time
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Published on: May 30, 2021

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分子动力学研究α-同核素域删除突变单体的研究

Noriyo Onishi1, Nicodemo Mazzaferro1, Špela Kunstelj1

  • 1Department of Chemistry, St. John's University, Queens, NY 11439, USA.

bioRxiv : the preprint server for biology
|April 8, 2024
PubMed
概括

错误折叠的α-synuclein (asyn) 聚合是帕金森病的关键. 了解asyn域如何相互作用,揭示了侧面域如何调节结构,可能影响蛋白质膜相互作用和疾病进展.

关键词:
跨领域的联系.本质上是无序的蛋白质.分子动力学分子动力学一个单质的单质分子.α-synuclein 是一种同核蛋白.

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