Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Oogenesis02:07

Oogenesis

63.7K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.7K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

2.7K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.7K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

4.6K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Discovery of a Unique NRPS Gene Cluster <i>San</i> for the Biosynthesis of Anti-Phytopathogenic and Cytotoxic Sansalvamides in the Endophytic <i>Fusarium</i> sp. R1.

Journal of agricultural and food chemistry·2026
Same author

Inhibition of Soluble Epoxide Hydrolase Rescues Cognitive Deficits by Preserving Neurovascular Integrity and Attenuating Glial- and Neuropathology in Diabetic-Related Dementia.

bioRxiv : the preprint server for biology·2026
Same author

The role of ultrasonography in diagnosing cystic adventitial disease.

Acta radiologica (Stockholm, Sweden : 1987)·2026
Same author

DCAF8 binds DDB1 via an N-terminal helix-loop-helix motif to assemble CRL4 and promote cell cycle progression.

Cell reports·2026
Same author

From Contact to Stalemate: MAPK-Associated Chemical and Enzymatic Defenses Shape a Stable Barrage in the Co-Culture of <i>Trametes</i> sp. D and <i>Aspergillus niger</i> L14.

Journal of fungi (Basel, Switzerland)·2026
Same author

Super-resolution multimodal spatial transcriptomics reveals an ovoid stem cell niche structuring de novo shoot regeneration.

Molecular plant·2026

相关实验视频

Updated: Jun 29, 2025

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
09:44

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model

Published on: March 5, 2022

3.0K

甲状腺功能和多囊卵巢综合征:孟德尔的随机化研究.

Zhendan Zhao1, Yuehua Gao1, Xiaoqing Pei1

  • 1Department of Ultrasound, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

Frontiers in endocrinology
|April 8, 2024
PubMed
概括

多囊卵巢综合征 (PCOS) 与甲状腺功能障碍的风险更高有关,这表明存在因果关系. 这项研究使用了门德尔的随机化来探索甲状腺功能和PCOS的联系.

关键词:
门德尔的随机化自由的甲状腺素是没有的.甲状腺功能过强症 甲状腺功能过强症甲状腺功能低下症 甲状腺功能低下症多囊性卵巢综合征多囊性卵巢综合征甲状腺刺激激素激素激发甲状腺刺激激素的激素.

更多相关视频

Author Spotlight: Investigating the Mechanisms and Inducing Models of Polycystic Ovary Syndrome
04:49

Author Spotlight: Investigating the Mechanisms and Inducing Models of Polycystic Ovary Syndrome

Published on: July 5, 2024

1.0K
A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
08:20

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

Published on: October 2, 2018

11.2K

相关实验视频

Last Updated: Jun 29, 2025

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
09:44

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model

Published on: March 5, 2022

3.0K
Author Spotlight: Investigating the Mechanisms and Inducing Models of Polycystic Ovary Syndrome
04:49

Author Spotlight: Investigating the Mechanisms and Inducing Models of Polycystic Ovary Syndrome

Published on: July 5, 2024

1.0K
A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
08:20

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

Published on: October 2, 2018

11.2K

科学领域:

  • 内分泌学 在内分泌学.
  • 生殖健康 生殖健康
  • 遗传学 是一个遗传学.

背景情况:

  • 多项研究表明甲状腺功能与多囊卵巢综合征 (PCOS) 之间的关系,但因果关系仍未得到证实.
  • 调查因果关系对于理解疾病机制和制定有针对性的干预措施至关重要.

研究的目的:

  • 为了确定甲状腺功能是否因果影响多囊卵巢综合征 (PCOS),使用孟德尔随机化.
  • 检查各种甲状腺功能表型和PCOS之间的潜在因果关系.

主要方法:

  • 进行了孟德尔随机化 (MR) 分析,使用来自大型全基因组关联研究 (GWAS) 的遗传数据.
  • 暴露变量包括正常的自由甲状腺素 (FT4),正常的甲状腺刺激激素 (TSH),甲状腺功能低下和甲状腺功能过高.
  • 结果变量是多囊性卵巢综合征 (PCOS),数据来自超过1600万个人. 反变量加权 (IVW) 方法是主要分析方法.

主要成果:

  • 在多囊性卵巢综合征 (PCOS) 和甲状腺功能障碍的风险增加之间发现了统计学上显著的关联 (IVW,OR=1.08,95%CI=1.02-1.13,P=0.004).
  • 与PCOS相关的其他甲状腺功能表型 (FT4,TSH,甲状腺功能低下) 没有发现显著的因果证据.

结论:

  • 这些发现提供了多囊性卵巢综合征 (PCOS) 和甲状腺功能障碍之间的因果关系的证据.
  • 这项研究为未来研究甲状腺功能与PCOS之间的复杂相互作用奠定了基础.