甲状腺激素与中国人甲状腺功能之间的关联:一个基于人口的横截面研究
Zheng-Xin Liu1, Jin-Lin Lv1, Yu-Luan Xiang1
1Department of Gerontology, The First Affiliated Hospital of Dali University, Dali, CHN.
Cureus
|April 8, 2024
概括
甲状腺激素会影响甲状腺功能不良的中国成年人的功能. 较低的自由三甲氨酸 (FT3) 和总三甲氨酸 (TT3) 水平,以及较高的甲状腺刺激激素 (TSH),与减少的膜过率 (GFR) 有关.
科学领域:
- 内分泌学 在内分泌学.
- 腎臟病學 (nephrology) 是一種醫學.
- 内部医学 内部医学
背景情况:
- 甲状腺激素和无甲状腺中国人的功能之间的关系还不清楚.
- 甲状腺功能障碍是慢性病 (CKD) 的已知危险因素.
研究的目的:
- 为了研究甲状腺激素水平与中国 euthyroid个体的功能之间的关联.
- 探索甲状腺激素与该人口中慢性病 (CKD) 风险之间的联系.
主要方法:
- 这是一项对661名中国甲状腺功能良好的个体进行的横截面研究.
- 评估膜过率 (GFR) 和尿中的白蛋白与肌素比率 (ACR).
- 经对共变量进行调整的统计分析,以确定甲状腺激素 (FT3,TT3,TT4,TSH) 和功能标志物之间的关联.
主要成果:
- 较高的自由三甲氨酸 (FT3) 和总三甲氨酸 (TT3) 水平与增加的GFR有关.
- 较高的甲状腺刺激激素 (TSH) 水平与GFR降低有关.
- 较高的TT3和总甲状腺素 (TT4) 水平与CKD风险降低有关,而与ACR没有发现任何关联.
结论:
- 甲状腺功能与甲状腺功能不良的中国人中的GFR显著相关.
- 较低的FT3,TT3和较高的TSH水平可能表明功能下降.
- 较低的TT3和TT4水平与CKD风险增加有关,这表明甲状腺激素在维持脏健康方面发挥了作用.
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