创伤性脑损伤患者脑静脉血栓症:流行病学和结果
Joao Meira Goncalves1,2, Vasco Carvalho1,2, António Cerejo1,2
1Neurosurgery Department, Centro Hospitalar Universitário de São João, Porto, PRT.
Cureus
|April 8, 2024
概括
创伤性脑静脉血栓症 (CVT) 经常发生在严重的创伤性脑损伤 (TBI) 和侧侧鼻血栓症中. 抗凝管理有所不同,在本研究中没有观察到显著的结果差异.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 流行病学 流行病学
背景情况:
- 创伤性脑静脉血栓塞 (CVT) 和其自然史仍然不太了解.
- 同时发生的内出血使创伤性CVT的治疗指南复杂化.
- 关于创伤性CVT的流行病学和管理的数据有限.
研究的目的:
- 描述创伤性CVT的人群特征.
- 审查创伤性CVT患者的医疗管理和结果.
- 分析创伤性脑损伤 (TBI) 相关的创伤性CVT的发生率和并发症.
主要方法:
- 对前性收集的放射学注册数据 (2016-2021) 的回顾性分析.
- 包括创伤性脑损伤 (TBI) 和通过CT静脉图像确认的CVT患者.
- 收集人口,临床,放射学数据,管理,并发症和结果 (出院时和3个月后的GOSE).
主要成果:
- 确定了41名创伤性CVT患者,主要是侧侧鼻血栓 (95%).
- 静脉梗塞是主要的并发症;60%的人患有封闭性静脉血栓.
- 78%的患者服用抗凝药,结果与未服用抗凝药的患者相比没有显著差异.
结论:
- 创伤性CVT在严重的TBI中更为常见,侧侧鼻的发病率显著,与头骨骨折有轻微的关联.
- 目前对创伤性CVT的治疗方法不一致,抗凝固药对这一队列的结果没有显著影响.
- 进一步的大规模,前性研究对于阐明创伤性CVT和建立基于证据的治疗指南至关重要.
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