心理社会因素和血糖控制在年轻的成年人与青年发病的2型糖尿病
Paula M Trief1, Hui Wen2, Brian Burke2
1Department of Psychiatry and Behavioral Sciences, State University of New York Upstate Medical University, Syracuse.
JAMA network open
|April 8, 2024
概括
心理社会因素,如糖尿病困扰和对药物的信仰,会影响青少年2型糖尿病的血糖控制. 解决这些因素的干预措施可能会改善2型糖尿病的年轻成年人的结果.
科学领域:
- 内分泌学和新陈代谢学
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 青少年发病的2型糖尿病 (T2DM) 与血糖控制不良和早期并发症有关.
- 识别心理社会因素对于在这个人群中开发有效的干预措施至关重要.
研究的目的:
- 为了研究心理社会因素和糖化血红蛋白 (HbA1c) 水平之间的关联,在年轻的成年人与青年发病的T2DM.
主要方法:
- 该iCount队列研究分析了348名年轻成年人 (平均年龄26.1岁) 患有青春期T2DM的数据.
- 在基线和1年随访期间测量HbA1c水平.
- 使用回归模型评估了心理社会因素 (关于药物的信念,痛苦,自我效能,支持) 和HbA1c之间的关联.
主要成果:
- 更高的相信糖尿病药物是必要的,对药物的担忧,以及糖尿病困扰与随访时高HbA1c的几率增加有关.
- 更大的自我管理支持和糖尿病自我有效性与高HbA1c的几率降低有关.
- 糖尿病困扰与较高的HbA1c水平相关.
结论:
- 心理社会因素,包括对药物的信仰,糖尿病困扰,自我效能和支持,与年轻人患有青春期T2DM的葡萄糖控制有显著关联.
- 针对这些心理社会方面的干预措施可以改善这种脆弱人群的血糖控制.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.3K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.3K
Diabetes: Symptoms, Diagnosis, and Complications
528
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
528
Diabetes Mellitus: Overview and Type I Subtype
2.6K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.6K
Diabetes: Management and Pharmacotherapy
275
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
275
Carbohydrate Metabolism
11.1K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.1K
Pathophysiology of Diabetes
924
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
924


