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Updated: Jun 29, 2025

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PVRL2通过PVRIG和TIGIT独立的途径抑制抗瘤免疫力

Jiuling Yang1, Li Wang1, James R Byrnes2

  • 1Department of Urology, University of California San Francisco, San Francisco, California.

Cancer immunology research
|April 8, 2024
PubMed
概括

与脊髓灰质炎病毒受体相关的2 (PVRL2) 作为癌症中的强有力的免疫检查点,抑制T和NK细胞. 用TIGIT阻塞准PVRL2显示出有效的癌症免疫疗法的显著前景.

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