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Updated: Jun 29, 2025

Sedimentation Equilibrium of a Small Oligomer-forming Membrane Protein: Effect of Histidine Protonation on Pentameric Stability
09:49

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Published on: April 2, 2015

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使用恒定pH的分子动力学模拟,识别影响人体血红蛋白T/R状态构造的histidine残留物

Shin-Ichi Fujiwara1, Kotaro Nishimura1, Kazuto Imamura1

  • 1Department of Biological Regulation, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan.

International journal of biological macromolecules
|April 8, 2024
PubMed
概括

研究人员在人体血红蛋白中确定了特定的histidine残留物,这些残留物在生理pH下影响其T状态和R状态的构成. 这一发现促进了对血红蛋白的理解.

关键词:
酸分离常数是酸分离的常数.血液中的血球蛋白.希斯蒂丁因 (Histidine) 是一种氨酸.分子动力学模拟模型质子化状态的状态.它们的pH值为pH.

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