吸收psilocybin后的动态功能超连接性主要与海洋无边界性有关.
Sepehr Mortaheb1, Larry D Fort1, Natasha L Mason2
1Physiology of Cognition, GIGA Research, CRC Human Imaging Unit, University of Liège, Liège, Belgium; Fund for Scientific Research FNRS, Brussels, Belgium.
概括
西改变了大脑的连接和主观经验,揭示了与深刻的心理变化相关的超连接大脑状态. 这项研究将大脑动态与迷幻体验联系起来,提供了新的见解.
科学领域:
- 神经科学是一个神经科学.
- 心理药理学 心理药理学
- 意识研究 意识研究
背景情况:
- 神经生物学与在迷幻状态中的主观体验之间的关系尚未得到充分理解.
- псилоцибин是一种已知的诱导改变意识状态的迷幻化合物.
- 之前的研究经常分别分析神经生物学和经验模式.
研究的目的:
- 为了调查神经生物学模式和主观经验之间的联系后,西宾管理.
- 探索动态大脑连接和追溯问卷数据之间的联系.
- 描述幻觉状态的神经经验相关的特征.
主要方法:
- 健康的参与者接受了psilocybin或安慰剂,并接受了7TMRI扫描.
- 在眼睛开放的休息状态下,在药物效果达到峰值时,评估了功能连接性.
- 五维意识改变状态评分表测量了主观经验.
主要成果:
- 西诱导大脑功能连接的广泛增加,并改变了主观经验的所有维度.
- 时间变化的分析揭示了与皮层激发升高相关的反复出现的超连接模式.
- 过渡到这种超连接状态的可能性增加与海洋无边界感和远见重组的感觉相关.
结论:
- 西会导致大脑功能和主观体验的显著变化.
- 在psilocybin下,超连接-超兴奋的大脑模式可能会促进新的心理关联.
- 研究结果阐明了大脑动态和主观经验之间的相互作用,提供了对幻觉状态的洞察.
关键词:
5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC 5D-ASC连接性的连接性动力学 动力学 动力学全球信号信号 全球信号信号这种药物是psilocybin.功能磁力共振成像 (fMRI) 是一种相关概念视频
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